{"id":563,"date":"2024-04-01T12:00:01","date_gmt":"2024-04-01T12:00:01","guid":{"rendered":"https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/?p=563"},"modified":"2025-05-15T14:43:36","modified_gmt":"2025-05-15T14:43:36","slug":"impact-on-healthcare-investing","status":"publish","type":"post","link":"https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/impact-on-healthcare-investing\/","title":{"rendered":"Good News! 100 Years of Progress &#8211; Impact on Healthcare Investing"},"content":{"rendered":"<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone size-full wp-image-568\" src=\"https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/doctors-working.jpg\" alt=\"doctors working\" width=\"800\" height=\"768\" srcset=\"https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/doctors-working.jpg 800w, https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/doctors-working-300x288.jpg 300w, https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/doctors-working-768x737.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<p>Not all prisoners are in jail and convicts aren&#8217;t the only people living with death sentences.\u00a0 Those with end stage organ failure and waiting for organ transplants celebrated another medical milestone with the transplantation of a genetically modified xeno pig\/human kidney in a living person experiencing renal failure.\u00a0 To get a sense of how momentus this development is we need to go back in time.<\/p>\n<h2><span style=\"font-size: 14pt\">A Century of Medical Milestones: From Artificial Hearts to Organ Transplants<\/span><\/h2>\n<p>Dr. Barney Clark was the first recipient of the Jarvik 7 artificial heart in 1982.\u00a0 This velcro and metal, air-powered contraption gave Dr. Clark a 112 day stay of execution.\u00a0 Artificial hearts are still seen as a bridge to transplantation rather than a permanent replacement.\u00a0 Organ transplantation remains the most successful approach to organ replacement, but a critical shortage of organs too often keeps patients on death row.\u00a0 Non-human organ transplantation has a long and disappointing history dating back to 1923 &#8211; organ rejection is the recurrent problem.<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-567\" src=\"https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/Jarvik-7.jpg\" alt=\"Jarvik 7\" width=\"800\" height=\"862\" srcset=\"https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/Jarvik-7.jpg 800w, https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/Jarvik-7-278x300.jpg 278w, https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/Jarvik-7-768x828.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<p>Jarvik 7, source:\u00a0<a href=\"https:\/\/blog.sciencemuseum.org.uk\/jarvik-7-an-artificial-heart\/\">https:\/\/blog.sciencemuseum.org.uk\/jarvik-7-an-artificial-heart\/<\/a><\/p>\n<h2><span style=\"font-size: 14pt\">The Breakthrough in Xenotransplantation: Genetically Modified Pig Kidney Transplant<\/span><\/h2>\n<p>Recent advances in gene editing are bringing new hope to the innocent.\u00a0 Last week, doctors at\u00a0Massachusetts General Hospital successfully completed a xenotransplantation of a genetically modified pig kidney into a patient in end stage renal failure.\u00a0 eGenesis, the creator of the kidney has this to say about it:<\/p>\n<p>The eGenesis donor kidney (EGEN-2784) used for this procedure is the company\u2019s lead candidate for kidney transplant and carries three classes of edits: (1) knock out of three genes involved in the synthesis of glycan antigens implicated in hyperacute rejection, (2) insertion of seven human transgenes involved in the regulation of pathways that modulate rejection: inflammation, innate immunity, coagulation, and complement, and (3) inactivation of the endogenous retroviruses in the porcine genome.\u00a0\u00a0<a href=\"https:\/\/egenesisbio.com\/press-releases\/egenesis-announces-worlds-first-successful-transplant-of-genetically-engineered-porcine-kidney-in-a-living-patient\/\">https:\/\/egenesisbio.com\/press-releases\/egenesis-announces-worlds-first-successful-transplant-of-genetically-engineered-porcine-kidney-in-a-living-patient\/<\/a><\/p>\n<p>eGenesis used CRISPR-Cas9 technology and made 69 genetic edits to the pig kidney, including removing harmful pig genes and adding certain human genes to enhance compatibility with humans.\u00a0 Without these edits the organ would have been rejected immediately!<\/p>\n<p>Think about it &#8211; a 100 years of experimentation has led to this moment.\u00a0 The next 5 years are likely to bring more advances than the previous 100 years combined.\u00a0 The general equation here seems to be:<\/p>\n<p><em>\u00a0Medicine\u00a0+ Technology = <strong>Exponential Improvement in Treatmen<\/strong>ts<\/em><\/p>\n<h2><span style=\"font-size: 14pt\">CRISPR and Genetic Editing: Paving the Way for Future Medical Advancements<\/span><\/h2>\n<p>CRISPR, the technology that allowed for the creation of this kidney will only improve from this point &#8211; probably by order of magnitude.\u00a0 The implications are more than financial &#8211; this technology is bringing something\u00a0priceless &#8211; hope!<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone size-full wp-image-568\" src=\"https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/doctors-working.jpg\" alt=\"doctors working\" width=\"800\" height=\"768\" srcset=\"https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/doctors-working.jpg 800w, https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/doctors-working-300x288.jpg 300w, https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/doctors-working-768x737.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<h2><span style=\"font-size: 14pt\">Healthcare and Biotechnology: A Winning Formula for Investors<\/span><\/h2>\n<p>So what does this mean for us as investors?\u00a0 Healthcare and biotechnology remain both fascinating and exceptional. The chart below shows the relative performance of Healthcare (orange), Biotech (purple) and the Toronto Stock Market (blue).<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-570\" src=\"https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/YCharts.jpg\" alt=\"YCharts\" width=\"800\" height=\"308\" srcset=\"https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/YCharts.jpg 800w, https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/YCharts-300x116.jpg 300w, https:\/\/advisor.wellington-altus.ca\/evansfamilywealth\/wp-content\/uploads\/sites\/205\/2024\/05\/YCharts-768x296.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<h2><span style=\"font-size: 14pt\">Biotech vs. Healthcare: What\u2019s Driving the Growth?<\/span><\/h2>\n<p>Take another look at the orange line &#8211; notice that the Healthcare Sector peaked in early 2022, and has been consolidating for two years prior to this year&#8217;s dash towards new all-time highs?\u00a0 We call that a price break-out.\u00a0 That&#8217;s typically a bullish sign.\u00a0 Comparing Healthcare to Biotech (purple line) you&#8217;ll notice that Biotech has had much greater swings and not nearly as high gains &#8211; that&#8217;s why I prefer Healthcare to Biotech.\u00a0 Finally, note that over the past\u00a0 ten years the Healthcare sector has outperformed the Toronto Stock Market (blue) by a huge margin.<\/p>\n<p>The Healthcare sector is like Vitamin C for your portfolio!<\/p>\n<p>Glen<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Not all prisoners are in jail and convicts aren&#8217;t the only people living with death sentences.\u00a0 Those with end stage organ failure and waiting for organ transplants celebrated another medical milestone with the transplantation of a genetically modified xeno pig\/human kidney in a living person experiencing renal failure.\u00a0 To get a sense of how momentus this development is we need to go back in time.<\/p>\n","protected":false},"author":193,"featured_media":568,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_oasis_is_in_workflow":0,"_oasis_original":0,"_oasis_task_priority":"","footnotes":""},"categories":[93],"tags":[395,403,394,20],"class_list":["post-563","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-insights-news","tag-healthcare-biotech","tag-portfolio-diversification","tag-technology-innovation","tag-wealth-management"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>100 Years of Progress - Impact on Healthcare Investing - Evans Family Wealth<\/title>\n<meta name=\"description\" content=\"Discover the groundbreaking success of genetically modified pig kidney transplants, marking a century of medical progress. 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